Efficacy of a single dose of esmolol to prevent extubation-related complications during emergence from anesthesia: a randomized, double-blind, placebo-controlled trial

Abstract Background Few trials have examined the efficacy of esmolol to attenuate hemodynamic and respiratory responses during extubation. However, the most appropriate dose of esmolol and an optimal protocol for administering this beta-blocker are uncertain. Methods Ninety patients ASA physical status I, II, and III (aged 18-60 years) scheduled to procedures with general anesthesia and tracheal extubation were selected. Patients were randomized into esmolol and placebo group to evaluate the efficacy and safety of a single bolus dose of esmolol (2 mg.kg-1) on cardiorespiratory responses during the peri-extubation period. The primary outcome was the rate of tachycardia during extubation. Results The rate of tachycardia was significantly lower in esmolol-treated patients compared to placebo-treated patients (2.2% vs. 48.9%, relative risk (RR): 0.04, 95% confidence interval (95% CI) = 0.01 to 0.32, p= 0.002). The rate of hypertension was also significantly lower in the esmolol group (4.4% vs. 31.1%, RR: 0.14, 95% CI 0.03 to 0.6, p= 0.004). Esmolol-treated patients were associated with higher extubation quality compared to patients who received placebo (p< 0.001), with an approximately two-fold increase in the rate of patients without cough (91.1%) in the esmolol group compared to the placebo group (46.7%). The rate of bucking was approximately 5-fold lower in the esmolol group (8.9% vs. 44.5%, respectively, RR: 0.20 (95% CI, 0.1 to 0.5, p= 0.002, with an NNT of 2.8). Conclusion A single bolus dose of esmolol is an effective and safe therapeutic strategy to attenuate cardiorespiratory responses during the peri-extubation period.

9p21 Locus Polymorphisms: Risk and Severity Factors of Coronary Artery Disease in Venezuelan Patients

Abstract Background: The 9p21 region is the most relevant locus associated with coronary heart disease in different populations. However, there are no studies that prove that this region is a risk factor in the Venezuelan population. Objectives: To analyze whether or not the 9p21 rs1333049 polymorphism is a risk factor for acute myocardial infarction (AMI) in Venezuelan patients, as well as to investigate its correlation with cardiovascular risk factors (CVRF), age of occurrence, type and severity of infarction, and the correlation of the rs10757274 polymorphism with severity of coronary artery disease. Methods: This was an association study, including 487 unrelated Venezuelan individuals, grouped in 354 patients with AMI and 133 controls. The rs1333049 and rs10757274 polymorphisms were determined using the polymerase chain reaction (PCR) technique with sequence-specific primers. The analysis of association was determined using the SNPStats tool. The continuous variable description and the correlations were performed using the SPSS statistical software. Significance was established at p<0.05. Results: A positive correlation was observed between the rs1333049 polymorphism and the presence of hypertension ( r: 0.145, p: 0.006), and between hypertension and heart infarction ( r: 0.318, p: <0.0001). A positive correlation was found between the rs10757274 polymorphism and the number of coronary vessels that presented obstructive lesions in patients aged ≤ 55 years ( r: 0.276, p: 0.0078). Conclusion: The rs1333049 polymorphism at the 9p21 locus is correlated with hypertension in Venezuelan patients, while the rs10757274 polymorphism is associated with the progression of coronary atherosclerosis, suggested by the correlation with the number of coronary vessels that presented significant obstructive lesions.

Drug Profile and Therapeutic Adherence of African-Brazilians with Apparent Resistant Hypertension

Abstract Background Resistant hypertension (RH) is manifested by the presence of blood pressure values resistant to antihypertensive therapy. RH is highly prevalent among black individuals, increasing cardiovascular risk in this population and requiring effective control of this comorbidity. Objectives To investigate the medication profile and therapeutic adherence in black people with apparent RH. Methods This is a cross-sectional study, with a convenience sample of individuals with apparent RH. Data were obtained from medical records. Therapeutic adherence was assessed using the Morisky Therapeutic Adherence Scale of 8 items (MMAS-8) and statistical analysis was performed using the SPSS, version 23. Significance was set at p <0.05. Results Of the 120 individuals, 90 (75%) were women and 72 (60%) were black. Mean SBP was 153.09 (SD 25.59) mm Hg and mean DBP, 90.82 (SD 16.91) mm Hg, with a statistical difference in relation to the target pressure for SBP. Regarding the medication profile, 79.2% of the individuals used the recommended regimen for RH (ACEI / ARB + Diuretic + CCB), with the fourth most used drug being beta-blockers. The average score in MMAS-8 was 6.62 (SD 1.38) points, with 19.2%, 50.0%, and 30.8% showing low, medium, and high adherence, respectively. Conclusions It was evidenced that two-thirds of the individuals did not have high therapeutic adherence and not all used the ideal regimen for the management of RH, nor full doses. Thus, most individuals were probably affected by pseudoresistance, which was initially diagnosed as apparent RH. (Int J Cardiovasc Sci. 2021; [online].ahead print, PP.0-0)

Factores de riesgo cardiovascular en Estados Unidos y México: comparación de los estudios HABLE y ENASEM / Cardiovascular risk factors in Mexico and the United States: a comparative cross-sectional study between the HABLE and MHAS participants

Resumen Introducción: En Estados Unidos se dispone de información acerca de la población mexicoamericana por el Estudio de Salud y Envejecimiento del Cerebro en Latinos Mayores (HABLE); en México se dispone de los resultados del Estudio Nacional de Salud y Envejecimiento en México (ENASEM). Objetivo: Comparar la prevalencia de factores de riesgo cardiovascular entre hombres y mujeres de HABLE y ENASEM. Método: Se analizó transversalmente la prevalencia de hipertensión, diabetes, hipercolesterolemia y obesidad abdominal en 559 participantes de HABLE y se comparó con datos de 13 663 participantes del ENASEM. La comparación se realizó mediante t de Student y chi cuadrada, según el tipo de variable. Resultados: El análisis demostró que la prevalencia de hipertensión (50 %, IC 95 % = 41.8-51.8), diabetes (35.5 %, IC 95 % = 27.6-43.8) y obesidad abdominal (59.3 %, IC 95 % = 50.5-68.1) fueron significativamente mayores en hombres del HABLE, mientras que las mujeres presentaron una prevalencia más elevada de diabetes (36.8 %, IC 95 % = 32.2-41.5) y obesidad abdominal (89.6 %, IC 95 % = 86.6-92.5). La hipercolesterolemia tuvo una prevalencia más elevada en mujeres del ENASEM (53.3 %, IC 95 % = 50.3-56.2). Conclusión: La prevalencia de factores de riesgo cardiovascular fue mayor en mexicoamericanos participantes del HABLE, que en mexicanos participantes del ENASEM.

Abstract Introduction: In the United States, information on the Mexican-American population is available through the Health and Aging Brain among Latino Elders (HABLE) study; in Mexico, the results of the Mexican Health and Aging Study (MHAS) are available. Objective: To compare the prevalence of cardiovascular risk factors between men and women of the HABLE and MHAS studies. Method: The prevalence of hypertension, diabetes, hypercholesterolemia and abdominal obesity was transversely analyzed in 559 HABLE participants and compared with data from 13,663 MHAS participants. The comparison was made using Student’s t-test and the chi-square test, according to the type of variable. Results: The analysis showed that the prevalence of hypertension (50 %, 95 % CI = 41.8-51.8), diabetes (35.5 %, 95 % CI = 27.6-43.8) and abdominal obesity (59.3 %, 95 % CI = 50.5-68.1) were significantly higher in HABLE males, whereas females had a higher prevalence of diabetes (36.8 %, 95 % CI = 32.2-41.5) and abdominal obesity (89.6 %, 95 % CI = 86.6-92.5). Hypercholesterolemia had a higher prevalence in MHAS females (53.3%, 95% CI = 50.3-56.2). Conclusion: The prevalence of cardiovascular risk factors was higher in Mexican American HABLE participants, than in Mexican MHAS participants.

Cardiovascular risk factors: differences between ethnic groups / Factores de riesgo cardiovascular: diferencias entre grupos étnicos / Fatores de risco cardiovascular: diferenças entre grupos étnicos

ABSTRACT Objectives: to compare the metabolic, anthropometric, tobacco and alcohol consumption indicators considered as risk factors for cardiovascular diseases, as well as the demographic and socioeconomic characteristics between indigenous from Rio Negro, Sateré-Mawé, mixed-race/black and white people living in the city of Manaus. Methods: a cross-sectional observational study guided by the STROBE tool. There was a sample of 191 adults of both sexes. Anthropometric measurements, blood pressure and biochemical analyzes were performed. Statistical test was applied to cross color/race/ethnicity variable with the investigated variables. Results: indigenous had better metabolic and anthropometric indicators related to cardiovascular diseases than mixed-race/black and white, as well as Sateré-Mawé in relation to Rionegrinos (from Rio Negro). Conclusions: the main differences were obesity, dyslipidemia, pre-systemic arterial hypertension/systemic arterial hypertension, and increased circumferences, with a worse situation for mixed-race/black people. The findings indicate differences in risk factors between race/color and ethnicity groups evaluated.

RESUMEN Objetivos: comparar los indicadores metabólicos, antropométricos, de consumo de tabaco y alcohol considerados como factores de riesgo para enfermedades cardiovasculares, así como las características demográficas y socioeconómicas entre los indígenas del Rio Negro, Sateré-Mawé, población de raza mixta/negra y blanca que viven en la ciudad de Manaus. Métodos: estudio observacional transversal, guiado por la herramienta STROBE. La muestra consistió en 191 adultos de ambos sexos. Se realizaron mediciones antropométricas, presión sanguínea y análisis bioquímicos. La prueba estadística se aplicó a la variable de color/raza/etnia con las variables investigadas. Resultados: los indígenas tenían mejores indicadores metabólicos y antropométricos relacionados con las enfermedades cardiovasculares que los de raza mixta/negros y blancos, así como los Sateré-Mawé en relación con los rionegrinos (del Rio Negro). Conclusiones: las principales diferencias fueron: obesidad, dislipidemia, pre-hipertensión arterial sistémica/ hipertensión arterial sistémica y aumento de las circunferencias, con una situación peor para los raza mixta/negros. Los resultados indican diferencias en los factores de riesgo entre los grupos de raza/color y etnia evaluados.

RESUMO Objetivos: comparar os indicadores metabólicos, antropométricos, de consumo de tabaco e álcool, considerados como fatores de risco para doenças cardiovasculares, assim como as características demográficas e socioeconômicas entre indígenas do Rio Negro, Sateré-Mawé, Pardos/Negros e Brancos que residem na cidade de Manaus. Métodos: estudo observacional transversal, norteado pela ferramenta STROBE. Amostra de 191 adultos de ambos os sexos. Realizadas medidas antropométricas, pressão arterial e análises bioquímicas. Aplicado teste estatístico no cruzamento da variável cor/raça/etnia com as variáveis investigadas. Resultados: os indígenas apresentaram melhores indicadores metabólicos e antropométricos relacionados às doenças cardiovasculares que os pardos/negros e brancos, assim como os Sateré-Mawé em relação aos rionegrinos. Conclusões: as principais diferenças foram: obesidade, dislipidemia, pré-hipertensão arterial sistêmica/hipertensão arterial sistêmica e circunferências aumentadas, com destaque de pior situação para os pardos/negros. Os achados indicam haver diferenças nos fatores de risco entre os grupos de raça/cor e etnia avaliados.

Prevalência autorreferida de hipertensão e fatores associados em comunidades quilombolas do Rio Grande do Sul, Brasil / Self-reported prevalence of hypertension and associated factors in quilombola communities in the State of Rio Grande do Sul, Brazil

Resumo Este estudo teve como objetivo identificar a prevalência e fatores associados à hipertensão arterial (HA) em adultos quilombolas do Rio Grande do Sul (RS). Trata-se de um estudo transversal de base populacional, realizado em 2011, com 589 adultos responsáveis por domicílios e amostragem proporcional ao tamanho. O desfecho foi obtido com a pergunta: "Algum médico já lhe disse que você tem hipertensão?". Foi empregada regressão de Poisson, com variância robusta e entrada hierarquizada das variáveis. Por fim, foram calculadas as frações atribuíveis populacionais por componente (FAPC) para fatores modificáveis associados à HA. A prevalência autorreferida de HA foi de 38,3% (IC95% 31,4%-45,1%). A análise ajustada revelou associação do desfecho com faixa etária, escolaridade, consumo excessivo de álcool, circunferência da cintura acima do adequado e presença de diabetes. A análise dos FAPC revelou que, se os indivíduos tivessem maior escolaridade, a prevalência de HA seria reduzida. Diante da elevada prevalência de HA e da extrema vulnerabilidade social dessa população, políticas públicas que garantam seu acesso a direitos fundamentais (saúde, renda e escolaridade) poderiam ter impacto importante na diminuição desse desfecho.

Abstract The study sought to identify the prevalence of arterial hypertension (AH) and possible associated factors in adults residing in quilombola communities in the State of Rio Grande do Sul (RS). A transversal population-based study, carried out in 2011, included 589 adult households in quilombola communities in the State of RS, by sampling proportional to the size. The outcome was obtained by the question: "Has a doctor ever told you that you have hypertension?" Poisson regression with robust variance and hierarchical input variables were used. Finally, the population attributable fractions per component (PAFC) were calculated for modifiable factors associated to AH. The self-reported prevalence of AH was 38.3% (CI95% 31.4%-45.1%). Adjusted analysis revealed an association of the outcome with age group, education, excessive alcohol consumption, waist circumference and the presence of diabetes. PAFC analysis revealed that if the individuals had greater schooling, the prevalence of AH would be reduced. Given the high prevalence of AH and the extreme social vulnerability of this population, public policies that guarantee their access to fundamental rights (health, income and schooling) could have a significant impact in reducing this outcome.

Prevalence, awareness, treatment and control of high blood pressure in the elderly according to the ethnic group. Colombian survey / Prevalencia, conocimiento, tratamiento y control de la presión arterial elevada en el adulto mayor de acuerdo con el grupo étnico. Encuesta colombiana salud, bienestar y envejecimiento 2015

Abstract Introduction: High blood pressure (HBP) is the main cardiovascular risk factor, it is more prevalent in the older adult population, and the prevalence can vary between ethnic groups. Objective: To estimate the prevalence of HBP, knowledge, treatment and control in population aged ≥60 years, resident in Colombia, according to their ethnic condition. Methods: Population sample selected by multistage sampling. Ethnicity was defined based on skin color. HBP was defined as systolic blood pressure ≥140, and/or diastolic blood pressure ≥90 mm Hg, and/or the participants' self-report. Controlled HBP at a blood pressure value <140/90, knowledge and treatment were identified by self-report. Results: 23,694 adults aged ≥60 years were included, of which 54.5%, 34.5% and 10.9% were respectively identified as having light, medium or dark skin color; 54.5% were women, and 78.1% resided in urban areas. The standardized prevalence of HBP, by age, was 57.7% (95% CI: 55.2-60.2); 51.4% (95% CI: 47.3-55.5), in men; and 62.9% (60.9-64.9), in women. The standardized prevalence for light, medium and dark skin in men was 53.2% (95% CI: 48.7-57.7), 49.6% (44.5-54.7), and 49.4% (95% CI: 41.0-57.8) respectively; and in women was 62.5% (95% CI: 60.5-64 , 5), 61.7% (95% CI: 57.8-65.6), and 69.9% (95% CI: 63.6-76.2) respectively. 98% of the population received treatment, and 93.9% were aware of HBP diagnosis. 42.5% of men and 55.5% of women with HBP were under control. Only 21.8% performed regular physical activity. Conclusion: Half of the adult population aged over 60 years suffers from HBP; the prevalence is higher in women particularly in dark-skinned women. It is necessary to develop policies to increase physical activity in the elderly.

Resumen Introducción: La presión arterial elevada (PAE) es el principal de factor de riesgo cardiovascular, es más prevalente en población adulta mayor y la prevalencia puede variar entre etnias. Objetivo: Estimar la prevalencia de PAE, conocimiento, tratamiento y control en población ≥60 años residente en Colombia de acuerdo con su condición étnica. Métodos: Muestra poblacional seleccionada mediante un muestreo multietápico. La etnia se definió con base en el color de piel. La PAE se definió como presión arterial sistólica ≥140 y/o presión arterial diastólica ≥90 mm Hg y/o el autoreporte del participante. La PAE controlada a un valor de presión arterial <140/90, el conocimiento y el tratamiento se identificaron por autoreporte. Resultados: Fueron incluidos 23,694 adultos con edad ≥ 60 años, de los cuales, 54.5%, 34.5% y 10.9% se identificaron con color de piel claro, medio u oscuro respectivamente, El 54.5%, eran mujeres y el 78.1% residía en zona urbana, La prevalencia estandarizada por edad de PAE fue 57,7% (IC 95%: 55.2-60.2), 51.4% (IC 95%: 4.3-55.5) en hombres y 62.9% (60.9-64.9) en mujeres, La prevalencia estandarizada en hombres claros, medios y oscuros fue 53.2%(IC 95%: 48.7-57.7), 49.6% (44.5-54.7) y 49.4% (IC 95%: 41.0-57.8) respectivamente y en mujeres 62.5% (IC 95%: 60.5-64.5), 61.7% (IC 95%: 57.8-65.6) y 69.9% (IC 95%: 63.6-76.2) respectivamente, El 98% de la población recibía tratamiento y el 93.9% conocía el diagnóstico de PAE, El 42.5% de los hombres y el 55.5% de las mujeres se encontraban con PAE controlada, El 21.8% realizaba actividad física regularmente. Conclusión: La mitad de la población adulta mayor a 60 años sufre PAE, mayor prevalencia en mujeres y particularmente mujeres oscuras. Se requiere desarrollar políticas para incrementar la actividad física en el adulto mayor.

Cardiovascular Risk in Xavante Indigenous Population / Risco Cardiovascular na População Indígena Xavante

Abstract Background: The prevalence of cardiovascular risk factors is little known in Brazilian indigenous populations. In the last two decades, important changes have occurred in the lifestyle and epidemiological profile of the Xavante people. Objective: to assess the prevalence of cardiovascular risk factors in Xavante adults in São Marcos and Sangradouro/Volta Grande reserves, in the state of Mato Grosso, Brazil. Methods: Cross-sectional study carried out with 925 Xavante people aged ≥ 20 years between 2008 and 2012. The following indicators were assessed: triglycerides (TG), total, LDL and HDL-cholesterol, Castelli index I and II, TG/HDL-cholesterol ratio, apo B / Apo A1 ratio, Framingham risk score, C-reactive protein, body mass index (BMI), waist circumference (WC), hypertriglyceridemic waist (HW), glycemia and blood pressure. Kolmogorov-Smirnov, Student's t test and Chi-square test (χ2) were used for statistical analysis, and significance level was set at 5%. Results: High prevalence of elevated cardiovascular risk was observed in men and women according to HDL-cholesterol (66.2% and 86.2%, respectively), TG (53.2% and 51.5%), TG/HDL-cholesterol ratio (60.0% and 49.1%), C-reactive protein (44.1% and 48.1%), BMI (81.3% and 81.7%), WC (59.1% and 96.2%), HW (38.0% and 50,6%) and glycemia (46.8% and 70.2%). Individuals aged 40 to 59 years had the highest cardiovascular risk. Conclusions: The Xavante have a high cardiovascular risk according to several indicators evaluated. The present analysis of cardiovascular risk factors provides support for the development of preventive measures and early treatment, in attempt to minimize the impact of cardiovascular diseases on this population.

Resumo Fundamento: A prevalência de fatores de risco cardiovascular ainda é pouco estudada em populações indígenas brasileiras. Nas duas últimas décadas, observaram- se importantes mudanças no estilo de vida e no perfil epidemiológico dos Xavante. Objetivo: Avaliar a prevalência de fatores de risco cardiovascular na população adulta Xavante das Reservas Indígenas de São Marcos e Sangradouro/Volta Grande - MT. Métodos: Estudo transversal realizado com 925 indígenas Xavante com 20 ou mais anos de idade, no período de 2008 a 2012. Foram considerados os indicadores: níveis séricos de triglicérides (TG), colesterol (total, LDL e HDL), Índices de Castelli I (CT/HDL-c) e II (LDL-c/HDL-c), razão TG/HDL-C, relação Apo B/Apo A1, escore de Framingham, proteína C reativa (PCR), Índice de Massa Corporal (IMC), circunferência da cintura (CC), cintura hipertrigliceridêmica (CH), glicemia e pressão arterial. Foram utilizados os testes Kolmogorov-Smirnov, t de Student e Qui quadrado (χ2), sendo considerado um nível de significância de 5%. Resultados: Verificaram-se altas prevalências de risco cardiovascular elevado, em homens e mulheres, respectivamente, segundo os indicadores HDL-colesterol (66,2% e 86,2%), TG (53,2% e 51,5%), razão TG/HDL-c (60,0% e 49,1%), PCR (44,1% e 48,1%), IMC (81,3% e 81,7%), CC (59,1% e 96,2%), CH (38,0% e 50,6%) e glicemia (46,8% e 70,2%). Os indivíduos de 40 a 59 anos foram os que apresentaram maior risco cardiovascular. Conclusões: Os Xavante apresentam elevado risco cardiovascular segundo vários indicadores avaliados. Este inquérito fornece subsídios para ações de prevenção e tratamento precoce, a fim de minimizar os potenciais danos causados por doenças cardiovasculares entre os Xavante.

Association between perceived racial discrimination and hypertension: findings from the ELSA-Brasil study / A associação entre discriminação racial percebida e hipertensão: achados do estudo ELSA-Brasil / Asociación entre la discriminación racial percibida y la hipertensión: hallazgos del estudio ELSA-Brasil

"Pardos" and blacks in Brazil and blacks in the USA are at greater risk of developing arterial hypertension than whites, and the causes of this inequality are still little understood. Psychosocial and contextual factors, including racial discrimination, are indicated as conditions associated with this inequality. The aim of this study was to identify the association between perceived racial discrimination and hypertension. The study evaluated 14,012 workers from the ELSA-Brazil baseline population. Perceived discrimination was measured by the Lifetime Major Events Scale, adapted to Portuguese. Classification by race/color followed the categories proposed by Brazilian Institute of Geography and Statistics (IBGE). Hypertension was defined by standard criteria. The association between the compound variable - race/racial discrimination - and hypertension was estimated by Poisson regression with robust variance and stratified by the categories of body mass index (BMI) and sex. Choosing white women as the reference group, in the BMI < 25kg/m2 stratum, "pardo" women showed adjusted OR for arterial hypertension of 1.98 (95%CI: 1.17-3.36) and 1.3 (95%CI: 1.13-1.65), respectively, whether or not they experienced racial discrimination. For black women, ORs were 1.9 (95%CI: 1.42-2.62) and 1.72 (95%CI: 1.36-2.18), respectively, for the same categories. Among women with BMI > 25kg/m2 and men in any BMI category, no effect of racial discrimination was identified. Despite the differences in point estimates of prevalence of hypertension between "pardo" women who reported and those who did not report discrimination, our results are insufficient to assert that an association exists between racial discrimination and hypertension.

Pretos e pardos no Brasil e negros nos Estados Unidos têm risco aumentado de desenvolver hipertensão arterial, quando comparados com brancos, mas as causas dessa desigualdade ainda são pouco compreendidas. Fatores psicossociais e contextuais, inclusive discriminação racial, têm sido apontados como condições associadas a essa desigualdade. O estudo teve como objetivo identificar a associação entre discriminação racial percebida e hipertensão. O estudo avaliou 14.012 participantes da linha de base do estudo ELSA-Brasil. A discriminação foi medida com a Lifetime Major Events Scale, adaptada para português. A classificação de raça/cor seguiu as categorias propostas pelo Instituto Brasileiro de Geografia e Estatística (IBGE). Hipertensão arterial foi definida de acordo com as diretrizes atuais. A associação entre a variável composta - raça/discriminação racial - e hipertensão foi estimada através de regressão de Poisson com variância robusta, e estratificada pelas categorias de índice de massa corporal (IMC) e gênero. Tendo como categoria de referência as mulheres brancas, no estrato de IMC < 25kg/m2, as mulheres pardas mostraram OR ajustada para hipertensão arterial de 1,98 (IC95%: 1,17-3,36) e 1,3 (IC95%: 1,13-1,65), respectivamente, conforme relatavam ou não a exposição à discriminação racial. Para as mulheres pretas, as ORs foram 1,9 (IC95%: 1,42-2,62) e 1,72 (IC95%: 1,36-2,18), respectivamente, para as mesmas categorias. Entre mulheres com IMC > 25kg/m2 e homens em qualquer categoria de IMC, não foi identificado nenhum efeito de discriminação racial. Apesar das diferenças nas estimativas pontuais da prevalência de hipertensão entre mulheres pardas que relataram (vs. não relataram) discriminação racial, nossos resultados são insuficientes para afirmar que existe uma associação entre discriminação racial percebida e hipertensão.

Los "mestizos" y negros in Brasil y los negros en los EE.UU. tienen un riesgo mayor de desarrollar hipertensión que los blancos, y las causas de esta inequidad se han estudiado poco. Factores psicosociales y contextuales, incluyendo la discriminación racial, han sido identificados como las condiciones asociadas a esta inequidad. El objetivo de este estudio fue identificar la asociación entre la discriminación racial percibida y la hipertensión. El estudio evaluó a 14.012 trabajadores procedentes de la base de referencia poblacional del ELSA-Brasil. La discriminación percibida se midió mediante la Lifetime Major Events Scale, adaptada al portugués. La clasificación por raza/color siguió las categorías propuestas por el Instituto Brasileño de Geografía y Estadística. La hipertensión fue definida por criterios estándar. La asociación entre la variable compuesta -raza/discriminación racial- e hipertensión se estimó por regresión de Poisson con varianza robusta y estratificada por las categorías: índice de masa corporal (IMC) y sexo. Se eligieron mujeres blancas como grupo de referencia, en el IMC < 25kg/m2 estrato, las mujeres "mestizas" mostraron una proporción de probabilidades ajustadas para hipertensión arterial de 1,98 (IC95%: 1,17-3,36) y 1,3 (IC95%: 1,13-1,65), respectivamente, hayan o no sufrido discriminación racial. Para las mujeres negras, la proporción de probabilidades ajustadas fueron 1,9 (IC95%: 1,42-2,62) y 1,72 (IC95%: 1,36-2,18), respectivamente, en las mismas categorías. Entre las mujeres con IMC > 25kg/m2 y hombres en cualquier categoría IMC, no se identificaron efectos de discriminación racial. A pesar de las diferencias en las estimaciones puntuales sobre la prevalencia de la hipertensión entre las mujeres "mestizas", que informaron y no informaron discriminación racial, nuestros resultados son insuficientes para afirmar que existe una asociación entre la discriminación racial e hipertensión.

Unawareness of hypertension and its determinants among 'quilombolas' (inhabitants of 'quilombos' - hinterland settlements founded by people of African origin) living in Southwest Bahia, Brazil / Desconhecimento da hipertensão arterial e seus determinantes em quilombolas do sudoeste da Bahia, Brasil

This study sought to evaluate the prevalence of unawareness of arterial hypertension (AH) and associated factors among the quilombola population and to describe aspects of the non-pharmacological management of AH. It involved a cross-sectional study with a sample of 358 people with AH aged 18 years or more. AH was considered systolic blood pressure (BP) ≥ 140 mmHg and/or diastolic blood pressure ≥ 90 mmHg and/or reported use of antihypertensive drugs. Unawareness of AH was classified as persons answering negatively when asked if they suffered from AH. Poisson regression was then used. The prevalence of unawareness of AH was 44.1% (95% CI: 38.9-49.3). Among those who already knew the diagnosis and had drug treatment only 24.8% had controlled BP. The unawareness of AH was positively associated with the male sex and Stage 1 of AH and negatively with increasing age, overweight, negative self-perception of health and medical visits. For non-pharmacological management, low percentages of quilombola reported appropriate standard recommendations of care. Arterial hypertension is a serious public health issue among the quilombola population, revealing great vulnerability in health due to poor levels of awareness, treatment and control.

Objetivou-se avaliar a prevalência de desconhecimento da hipertensão arterial (HA) e fatores associados em quilombolas e descrever aspectos do manejo não farmacológico da HA. Estudo transversal com amostra de 358 indivíduos hipertensos com 18 anos ou mais, definida como aqueles com pressão arterial (PA) sistólica ≥ 140mmHg e/ou pressão arterial diastólica ≥ 90 mmHg e/ou relataram uso de medicamentos anti-hipertensivos. Foram classificados com desconhecimento da HA aqueles que responderam negativamente a pergunta sobre conhecer o diagnóstico de HA. Empregou-se regressão de Poisson. A prevalência de desconhecimento da HA foi de 44,1% (IC95%: 38,9-49,3). Entre os que já sabiam do diagnóstico e estavam em tratamento medicamentoso apenas 24,8% tinha a PA controlada. O desconhecimento da HA associou-se positivamente com sexo masculino e estágio 1 da HA e, negativamente, com maior faixa etária, sobrepeso, autopercepção negativa da saúde e realização de consulta médica. Para o manejo não farmacológico foi observado baixos percentuais de solicitação de exames e seguimento das recomendações adequadas. A HA destaca-se como um problema de saúde pública nesta população, descortinando grande vulnerabilidade em saúde devido aos níveis insatisfatórios de conhecimento, tratamento e controle.

Epidemiology of high blood pressure among the Kaingang people on the Xapecó Indigenous Land in Santa Catarina State, Brazil, 2013 / Epidemiologia da hipertensão arterial em indígenas Kaingang, Terra Indígena Xapecó, Santa Catarina, Brasil, 2013 / Epidemiologia da hipertensão arterial em indígenas Kaingang, Terra Indígena Xapecó, Santa Catarina, Brasil, 2013 / Epidemiología de la hipertensión en los indígenas Kaingang, Tierra Indígena Xapecó, Santa Catarina, Brasil, 2013

This cross-sectional study describes the prevalence of high blood pressure (HBP; measured at one setting, and suggestive of a clinical diagnosis of arterial hypertension) and mean systolic blood pressure (SBP) and diastolic blood pressure (DBP) and their associations with socio-demographic and anthropometric variables among 355 Kaingang adults (≥ 20 years) on the Xapecó Indigenous Land in Brazil. Weight, height, waist circumference (WC), SBP, and DBP were measured and socio-demographic data were collected. Prevalence of HBP was 53.2% (95%CI: 45.3; 61.1) in men and 40.7% (95%CI: 33.8; 47.6) in women. In women, age and WC were directly associated with HBP; age was associated with SBP and schooling with DBP. In men, HBP was statistically associated with high body mass index (BMI) and tile floor in the home (as a socioeconomic proxy); BMI and WC were associated with SBP; BMI and WC were associated with DBP. The study highlights the need for measures to control risk factors for HBP, especially due to its relevance for cardiovascular diseases and their consequences.

Estudo transversal, com objetivo de descrever a prevalência de níveis tensionais sugestivos de hipertensão arterial sistêmica (NTSHAS), e das médias de pressão arterial sistólica (PAS) e diastólica (PAD), e suas associações com dados sociodemográficos e antropométricos, entre 355 adultos (20+ anos) Kaingang (Terra Indígena Xapecó). Foram aferidos peso, estatura, circunferência da cintura (CC), PAS, PAD, e coletados dados sociodemográficos. A prevalência de níveis tensionais sugestivos de hipertensão foi 53,2% (IC95%: 45,3; 61,1) entre os homens e 40,7% (IC95%: 33,8; 47,6) entre as mulheres. Nas mulheres, a idade e CC se associaram positivamente aos NTSHAS; a idade se associou à PAS e a escolaridade à PAD. Nos homens com maior índice de massa corporal (IMC) e CC e casa com chão de cerâmica, registraram-se maiores prevalências de níveis tensionais sugestivos de hipertensão; a maior CC e maior IMC se associaram com valores mais altos de PAS; o IMC e a CC, diretamente com a PAD. Destaca-se a necessidade de ações para controle dos fatores de risco para NTSHAS, por causa da elevada prevalência encontrada entre os Kaingang e a contribuição na morbimortalidade por doenças cardiovasculares.

Estudo transversal, com objetivo de descrever a prevalência de níveis tensionais sugestivos de hipertensão arterial sistêmica (NTSHAS), e das médias de pressão arterial sistólica (PAS) e diastólica (PAD), e suas associações com dados sociodemográficos e antropométricos, entre 355 adultos (20+ anos) Kaingang (Terra Indígena Xapecó). Foram aferidos peso, estatura, circunferência da cintura (CC), PAS, PAD, e coletados dados sociodemográficos. A prevalência de níveis tensionais sugestivos de hipertensão foi 53,2% (IC95%: 45,3; 61,1) entre os homens e 40,7% (IC95%: 33,8; 47,6) entre as mulheres. Nas mulheres, a idade e CC se associaram positivamente aos NTSHAS; a idade se associou à PAS e a escolaridade à PAD. Nos homens com maior índice de massa corporal (IMC) e CC e casa com chão de cerâmica, registraram-se maiores prevalências de NTSHAS; a maior CC e maior IMC se associaram com valores mais altos de PAS; o IMC e a CC, diretamente com a PAD. Destaca-se a necessidade de ações para controle dos fatores de risco para NTSHAS, por causa da elevada prevalência encontrada entre os Kaingang e a contribuição na morbimortalidade por doenças cardiovasculares.

Estudio transversal, con el objetivo de describir la prevalencia de niveles tensionales sugestivos de la hipertensión arterial sistémica (NTSHAS), los niveles de presión arterial sistólica (PAS) y diastólica (PAD), y su asociación con datos sociodemográficos y antropométricos, entre 355 adultos (20+años) Kaingang (Tierra Indígena Xapecó). Se midieron peso, talla, circunferencia de cintura (CC), PAS y PAD, y se recogieron datos sociodemográficos. La prevalencia de HAS fue 53,2% (IC95%: 45,3; 61,1) entre los hombres y 40,7% (IC95%: 33,8; 47,6) en las mujeres. En ellas, la edad y la CC se asociaron positivamente a NTSHAS; la edad se asoció con la PAS y la escolaridad con la PAD. En hombres de mayor índice de masa corporal (IMC) y CC, y con casa de pisos de cerámica, se registraron mayor prevalencia de HAS; la mayor CC y mayor IMC se asociaron con mayor PAS; y el IMC y CC, directamente asociados con la PAD. Destaca la necesidad de adoptar medidas dirigidas a controlar los factores de riesgo para la NTSHAS, en vista de la alta prevalencia entre los Kaingang y su contribución en la morbilidad y la mortalidad por enfermedad cardiovascular.

Comunidades quilombolas de Vitória da Conquista, Bahia, Brasil: hipertensão arterial e fatores associados / Quilombo communities in Vitória da Conquista, Bahia State, Brazil: hypertension and associated factors / Comunidades quilombolas de Vitória da Conquista, Bahía, Brasil: hipertensión y factores asociados

Este estudo objetivou estimar a prevalência de hipertensão arterial em residentes das comunidades quilombolas e avaliar possíveis fatores associados. Foi realizado um inquérito de base populacional em uma amostra de 797 indivíduos com 18 anos ou mais. A hipertensão arterial foi definida por pressão arterial sistólica > 140mmHg e/ou pressão arterial diastólica > 90mmHg e/ou uso de medicamentos anti-hipertensivos. Empregou-se a regressão de Poisson com variância robusta, adotando a entrada hierárquica de variáveis. A prevalência de hipertensão foi de 45,4% (IC95%: 41,89-48,85), o fator distal: segurança na vizinhança; os fatores intermediários: idade, classe econômica, escolaridade e inatividade física; e o fator proximal: índice de massa corporal mostraram-se associados com a hipertensão. Observa-se a necessidade da promoção da saúde por meio de atenção inclusiva aos quilombolas, valendo-se de ações em níveis individual e populacional. A alta prevalência de hipertensão arterial reforça a necessidade de um amplo acesso aos serviços de saúde para prevenção, diagnóstico precoce e orientações para o manejo adequado.

The study aimed to estimate the prevalence of hypertension in members of quilombos (slavedescendant African-Brazilian communities) and to evaluate possible associated factors. A population-based survey included 797 individuals 18 years or older. Hypertension was defined as systolic blood pressure > 140mmHg or diastolic blood pressure > 90mmHg or reported use of antihypertensive medication. We used Poisson regression with robust variance and hierarchical entry of variables. Prevalence of hypertension was 45.4% (95%CI: 41.89-48.85). Factors associated with hypertension were: neighborhood security (distal), age, economic class, education, and physical inactivity (intermediate), and body mass index (proximal). Health promotion is needed in the quilombo communities through action at the individual and population levels. The high prevalence of hypertension highlights the need for broad access to health services for prevention, early diagnosis, and guidelines for adequate management.

El objetivo de este estudio fue estimar la prevalencia de hipertensión arterial de residentes de las comunidades quilombolas y evaluar sus factores asociados. Es un estudio basado en la población, con una muestra de 797 individuos de 18 años o más. La hipertensión arterial se define como una presión arterial sistólica > 140mmHg y/o presión arterial diastólica > 90mmHg y/o el uso de medicamentos antihipertensivos. Se utilizó la regresión de Poisson con varianza robusta, con una entrada jerárquica de variables. La prevalencia de hipertensión arterial fue de 45,4% (95%IC: 41,89-48,85), los factores distales: la seguridad en el barrio, factores intermedios: edad, clase socioeconómica, la educación y la falta de actividad física, factores proximales como el índice de masa corporal estaban asociados con la hipertensión arterial. Existe la necesidad de promover la salud mediante la atención inclusiva de los quilombolas a través de acciones a nivel individual y poblacional. La alta prevalencia de la hipertensión arterial aumenta la necesidad de acceso a los servicios de salud para la prevención, el diagnóstico precoz y las directrices para una gestión adecuada.

Anthropometry and blood pressure changes in a caribbean adolescent population of african ancestry: an evaluation of longitudinal data using a multilevel mixed regression approach / Antropometría y cambios de presión sanguínea en una población adolescente caribeña de ascendencia africana: evaluación de datos longitudinales en un enfoque de regresión multinivel mixto

OBJECTIVE: The aim of this study was to determine the effect of growth pattern on blood pressure changes in an adolescent population of African ancestry based on longitudinal data and to compare this with estimates derived from cross-sectional data. METHODS: Participants had measurements of weight, height, blood pressure and percentage body fat taken annually using standardized procedures. Annual blood pressure and anthropometry velocities as well as one- and three-year interval gender specific tracking coefficients were computed. We investigated whether changes in blood pressure could be explained by measures of growth using a multilevel mixed regression approach. RESULTS: The results showed that systolic blood pressure (SBP) increased by 1.27 and 3.09 mmHg per year among females and males, respectively. Similarly, diastolic blood pressure (DBP) increased by 1.16 and 1.92 mmHg per year among females and males, respectively. Multilevel analyses suggested that weight, body mass index, percentage body fat and height were the strongest anthropometric determinants of blood pressure change in this population. The results also suggest that there are gender differences in the relative importance of these anthropometric measures with height playing a minor role in predicting blood pressure changes among adolescent females. With the exception of DBP at 18 years among females, there were no significant differences between mean blood pressure generated from cross-sectional and longitudinal data by age in both males and females. CONCLUSION: Anthropometric measures are important covariates of age-related blood pressure changes and cross-sectional data may provide a more cost-effective and useful proxy for generating age-related blood pressure estimates in this population.

OBJETIVO: El objetivo de este estudio fue determinar el efecto del patrón de crecimiento sobre los cambios de presión sanguínea en una población juvenil de ascendencia africana sobre la base de datos longitudinales, y comparar esto con los estimados derivados de los datos transversales. MÉTODOS: A los participantes se les hicieron mediciones de peso, altura, presión sanguínea, y porcentaje de grasa corporal, las cuales fueron realizadas anualmente mediante procedimientos estandarizados. Se computarizaron la presión sanguínea anual y las velocidades de la antropometría así como los coeficientes de rastreo específicos de género en intervalos de uno y tres años. Se investigó si los cambios de presión sanguínea podrían explicarse por las medidas de crecimiento, usando un enfoque de regresión multinivel mixto. RESULTADOS: Los resultados mostraron que la presión sanguínea sistólica (PSS) aumentaba en 1.27 y 3.09 mmHg por año entre las hembras y los varones respectivamente. De modo similar, la presión sanguínea diastólica (PSD) aumentaba en 1.16 y 1.92 mmHg por año entre las hembras y varones respectivamente. Los análisis multiniveles sugirieron que el peso, el índice de masa corporal, el porcentaje de grasa corporal y la altura, fueron los determinantes antropométricos más fuertes del cambio de presión sanguínea en esta población. Los resultados también sugieren que hay diferencias de género en la importancia relativa de estas mediciones antropométricas, siendo el caso que la altura juega un papel menor a la hora de predecir los cambios de presión sanguínea entre las adolescentes. Con excepción de la PSD a los 18 años entre las hembras, no hubo ninguna diferencia significativa entre la presión sanguínea promedio obtenida a partir de los datos transversales y longitudinales por edad, tanto en los varones como en las hembras. CONCLUSIÓN: Las medidas antropométricas son covariantes importantes de los cambios de presión sanguínea relacionadas con la edad. Los datos transversales pueden ofrecer un recurso útil y costo-efectivo para producir estimados de la presión sanguínea relacionada con la edad en esta población.

Prevalencia de hipertensión arterial en comunidades pehuenches, Alto Biobio / Prevalence of hypertension in Pehuenche communities living in the area of Alto Bio Bio Chile

Antecedentes: En los últimos años se ha observado un aumento en la prevalência de hipertensión arterial (HTA), que incluso afecta a población rural e indígena. Sin embargo, no existen datos de la población pehuen-che, la que habita mayoritariamente en la comuna de Alto Biobio. Objetivos: Determinar la prevalencia de HTA en habitantes de comunidades pehuenches y su relación con características etnodemográficas y el estado nutricional. Métodos: Estudio de prevalencia, corte transversal, sobre una muestra de 400 individuos mayores de 15 años; la adquisición de datos se realizó entre mayo y octubre de 2011. Se incluyen variables sociodemográficas, étnicas y clínicas, estas últimas de acuerdo a criterios diagnósticos del MINSAL. Resultados: La prevalencia de HTA corresponde al 24,5 por ciento; no pesquisamos diferencias estadísticamente significativas por sexo, etnia ni estado nutricional. En cambio, si las hubo por edad, donde las personas mayores tenían una mayor prevalencia y gravedad de HTA que sus contrapartes más jóvenes; el 70,59 por ciento de los mayores de 65 años tenía HTA. De la misma forma, se aprecia un aumento progresivo de las presiones diastólicas, sistólicas y medias con la edad. Solo el 32 por ciento de la población previamente diagnosticada tenía presiones en rango normal. Conclusiones: La prevalencia de HTA en comunidades pehuenches es similar a la nacional, siendo la edad el único factor de riesgo asociado a este diagnóstico.

The prevalence hypertension is increasing in general, including the rural and native populations of Chile. However, there is no information regarding this problem in the Pehuenche population, which inhabits the High BioBio area. Aim: to determine the prevalence of hypertension in Pehuenche communities and its relation to ethnic, demographic and nutritional factors Methods: A cross sectional sample of 400 individuals 16 years and older were surveyed between May and October 2011. Socio-demographic, ethnic and clinical characteristics were assessed. The National Health Department's definitions were used. Results: Hypertension was found in 24.5 percent of subjects. There were no differences in the prevalence of hypertension according to gender, ethnic factors or nutritional state. As expected, prevalence of hypertension increased with age, reaching 70.6 percent in those above 65 years. Both systolic and diastolic pressures increased with age. Only 32 percent of the previously evaluated subjects had a normal blood pressure. Conclusion: the prevalence of Hypertension in pe-huenches is similar to that observed in the overall Chilean population. There was no relation of hypertension prevalence to ethnic or nutritional factors.

The epidemiology of end stage renal disease at a centre in Trinidad / Epidemiología de la fase terminal de la enfermedad renal en un centro de Trinidad

OBJECTIVE: The aim of this study is to estimate the trends in prevalence of end stage renal disease (ESRD) during the period 1999-2007 at one site in Trinidad, the Eric Williams Medical Sciences Complex (EWMSC), and to describe the epidemiological features, age, gender, ethnicity and co-morbidities associated with ESRD. DESIGN AND METHODS: A retrospective cohort study design was used. There was a count of patients on haemodialysis at the EWMSC centre from 1999 - 2007 in order to demonstrate trends in prevalence but more detailed data were collected and analysed for patients with ESRD attending the nephrology clinic between January 2002 and December 2007. The data that were collected from the patients' records included: demographic data (age, gender and ethnicity), medical history (diabetes mellitus, hypertension, end stage renal disease and autoimmune disorders), history of dialysis (type of vascular access, frequency of dialysis), mortality and its cause. RESULTS: Records of 81 patients were retrieved. Their age range was 10-79 years. The survey showed that patients most affected in the study population were: males, aged 50-59 years, who were hypertensive and/or diabetic and of African descent. CONCLUSIONS: In conclusion, we provide epidemiological evidence of ESRD and the associated contributing factors at one hospital in Trinidad.

OBJETIVO: El objetivo de este estudio es estimar las tendencias de la prevalencia de la enfermedad renal en fase terminal (ERFT) durante el periodo 1999-2007 en el Complejo de Ciencias Médicas Eric Williams, en Trinidad, y describir los rasgos epidemiológicos - edad, género, etnicidad - y co-morbilidades asociadas con la ERFT. DISEÑO Y MÉTODOS: Se usó un diseño de estudio de cohorte retrospectivo. Se llevó a cabo un análisis de todos los pacientes que asistieron a las clínicas de nefrología de EWMSC, de enero de 2002 a diciembre de 2007. Los datos recogidos de las historias clínicas de los pacientes al final del período de estudio incluyeron: datos demográficos (edad, género y etnicidad), historia médica (diabetes mellitus, hipertensión, enfermedad renal en fase terminal, trastornos autoinmunes), historia de diálisis (tipo de acceso vascular, frecuencia de diálisis), mortalidad y causa. RESULTADOS: Se obtuvieron las historias clínicas de 81 pacientes, cuya edad fluctuaba de 10 a 79 años. La encuesta mostró que los pacientes más afectados en la población del estudio fueron varones, de 50-59 años de edad, que eran hipertensos y/o diabéticos, de ascendencia africana. CONCLUSIONES: En conclusión, se ofrece evidencia epidemiológica de la ERFT en un hospital en Trinidad y se señalan los factores asociados que contribuyen a la enfermedad.

Frequency and Related Factors of Masked Hypertension at a Worksite in Korea / 예방의학회지

OBJECTIVES: Masked hypertension is associated with metabolic risks and increased risk of cardiovascular disease. The purpose of this study was to identify the frequency of and risk factors of masked hypertension in Korean workers. METHODS: The study was conducted among 121 employees at a hotel in Gyeongju, Korea, from December 2008 to February 2009. We measured blood pressure (BP) both in the clinic and using 24-hour ambulatory BP monitors for all subjects. Hypertension was defined independently by both methods, and subjects were classified into four groups: true normotension, masked hypertension, white coat hypertension, and sustained hypertension. RESULTS: The frequency of masked hypertension in our study group was 25.6%. Compared with true normotension, the factors related to masked hypertension were male gender (odds ratio [OR], 10.7; 95% confidence interval [CI], 1.41 to 81.09), aging one year (OR, 0.88; 95% CI, 0.78 to 0.99), clinic BP 120-129/80-84 mmHg (OR, 8.42; 95% CI, 1.51 to 46.82), clinic BP 130-139 / 85-89 mmHg (OR, 12.14; 95% CI, 1.80 to 81.85), smoking (OR, 5.51; 95% CI, 1.15 to 26.54), and increase of total cholesterol 1 mg / dL (OR, 1.05; 95% CI, 1.02 to 1.08). In males only, these factors were clinic BP 120-129 / 80-84 mmHg (OR, 15.07; 95% CI, 1.55 to 146.19), clinic BP 130-139 / 85-89 mmHg (OR, 17.16; 95% CI, 1.56 to 189.45), smoking (OR, 11.61; 95% CI, 1.52 to 88.62), and increase of total cholesterol 1 mg/dL (OR, 1.05; 95% CI, 1.01 to 1.09). CONCLUSIONS: The frequency of masked hypertension was high in our study sample. Detection and management of masked hypertension, a known strong predictor of cardiovascular risk, could improve prognosis for at-risk populations.

Blood pressure control, hypertension, awareness, and treatment in adults with diabetes in the United States-Mexico border region / Control de la presión arterial, hipertensión, concientización y tratamiento en adultos con diabetes de la zona fronteriza entre México y los Estados Unidos

OBJETIVE: To determine prevalence of blood pressure control, hypertension, hypertension awareness, and antihypertensive treatment among adults (> 18 years old) with diabetes living in the border region between the United States of America and Mexico, and to explore variation in those variables between all adults on the Mexican side of the border ("Mexicans") and three groups on the U.S. side of the border ("all U.S. adults," "U.S.-born Hispanics," and "Mexican immigrants"). METHODS: Using data from Phase I (February 2001-October 2002) of the U.S.-Mexico Border Diabetes Prevention and Control Project, a prevalence study of type 2 diabetes and its risk factors, age-adjusted prevalence of hypertension-related variables was calculated for the sample (n = 682) and differences between the border groups were examined through logistic regression. RESULTS: Less than one-third of the sample had controlled blood pressure (< 130/80 mm Hg), almost half had hypertension (>140/90 mm Hg), and hypertension awareness and treatment were inadequate. After adjusting for demographics, body mass index, and access to health care, there were no differences in blood pressure control, hypertension, hypertension awareness, or treatment between Mexicans and both U.S. adults and Mexican immigrants. However, compared to Mexicans and Mexican immigrants, U.S.-born Hispanics, particularly younger individuals, had the lowest rates of blood pressure control (17.3 percent) and the highest rates of coexisting hypertension (54.8 percent). Compared to Mexicans, U.S.-born Hispanics had lower odds of controlled blood pressure (odds ratio [OR] 0.30, 95 percent confidence interval [CI] 0.09-0.95) and greater odds of hypertension (OR 3.75, 95 percent CI 1.51-9.29) and hypertension awareness (OR 6.19, 95 percent CI 1.46-26.15). CONCLUSION: Co-occurrence of diabetes and hypertension is a major public health problem among U.S.-Mexico border residents. The low rate of blood pressure control among various border groups, especially younger U.S.-born Hispanics, suggests that initiatives should aggressively target blood pressure control.

OBJETIVO: Determinar la prevalencia del control de la presión arterial, la hipertensión, la concientización en materia de hipertensión y el tratamiento antihipertensivo entre los adultos (> 18 años) con diabetes residentes en la zona fronteriza entre México y los Estados Unidos, y analizar las diferencias de esas variables en todos los adultos del lado mexicano de la frontera ("mexicanos") y tres grupos del lado estadounidense ("todos los adultos estadounidenses", "los hispanos nacidos en los Estados Unidos" y "los inmigrantes mexicanos"). MÉTODOS: A partir de los datos de la primera fase (febrero del 2001 a octubre del 2002) del Proyecto de Prevención y Control de la Diabetes en la Frontera México- Estados Unidos, un estudio sobre la prevalencia de la diabetes tipo 2 y sus factores de riesgo, se calculó en la muestra (n = 682) la prevalencia ajustada por edad de las variables relacionadas con la hipertensión, y se analizaron las diferencias entre los grupos fronterizos mediante regresión logística. RESULTADOS: Menos de un tercio de la muestra tenía una presión arterial controlada (< 130/80 mm de Hg), casi la mitad presentaba hipertensión (> 140/90 mm de Hg), y la concientización y el tratamiento de la hipertensión eran inadecuados. Tras el ajuste en cuanto a los factores demográficos, el índice de masa corporal y el acceso a la atención de salud, no se observaron diferencias en cuanto al control de la tensión arterial (normotensión), la hipertensión, la concientización en materia de hipertensión o el tratamiento entre los mexicanos y los adultos estadounidenses o los inmigrantes mexicanos. Sin embargo, en comparación con los mexicanos y los inmigrantes mexicanos, los hispanos nacidos en los Estados Unidos, en particular los más jóvenes, presentaban las menores tasas de presión arterial normal (17,3 por ciento) y las mayores tasas de hipertensión coexistente (54,8 por ciento). En comparación con los mexicanos, la probabilidad de tener una tensión arterial normal era menor entre los hispanos nacidos en los Estados Unidos (razón de posibilidades [OR] 0,30, intervalo de confianza [IC] 95 por ciento 0,09-0,95), y eran mayores las probabilidades de hipertensión (OR 3,75, IC 95 por ciento 1,51-9,29) y concientización en materia de hipertensión (OR 6,19, IC 95 por ciento 1,46-26,15). CONCLUSIONES: La coexistencia de diabetes e hipertensión constituye un importante problema de salud pública en los residentes de la zona fronteriza entre México y los Estados Unidos. La baja tasa de normotensión entre los diversos grupos fronterizos, especialmente en los jóvenes hispanos nacidos en los Estados Unidos, indica que se deben llevar a cabo iniciativas dirigidas enérgicamente hacia el control de la presión arterial.

Itinerários terapêuticos face à hipertensão arterial em famílias de classe popular / Experience with treatment of high blood pressure in low-income families

Na compreensão sobre a hipertensão arterial sistêmica (HAS) é importante considerar a influência dos conhecimentos e crenças associados à doença, bem como, os recursos disponíveis para o seu tratamento. Este trabalho analisa itinerários terapêuticos de três famílias de classe popular do tipo extensa que possuíam portadores de HAS. Investigou-se as alternativas adotadas, os determinantes das escolhas, a avaliação sobre os serviços utilizados e os reflexos da interação com os serviços no cuidado doméstico. Foi realizado um estudo etnográfico em um bairro popular de Salvador por meio de observação e entrevistas semi-estruturadas com informantes em espaços domiciliares e institucionais. Constatou-se que os itinerários das famílias participantes não seguiam um padrão rígido, sendo influenciados pelas experiências prévias com a hipertensão e outras doenças, pelo suporte social disponível e pelas condições do atendimento do sistema formal no bairro. Observou-se, também, a apropriação e adaptação do conhecimento técnico de saúde pelos grupos familiares.

In order to properly understand high blood pressure (HBP), or arterial hypertension, it is important to examine the influence of knowledge and beliefs associated with the condition, as well as the resources available for its treatment. This study analyzes the treatment experiences of three low-income extended families that include members with HBP. The study investigated the various alternatives that were adopted, determinants of choices, evaluation of the services used, and the impact of interaction with health services on care in the home. An ethnographic study was performed in a low-income neighborhood in Salvador, Bahia State, using direct observation and semi-structured interviews with key informants in home and institutional settings. The study found that the treatment experiences of the participating families did not follow a rigid pattern, but were influenced by prior experiences with hypertension and other diseases, available social support, and conditions in the formal health care system available in the neighborhood. The study also detected a grasp and adaptation of technical health knowledge by families.

Hipertensão endócrina em adultos / Endocrine hypertension in adults

Apesar da grande maioria dos pacientes apresentarem hipertensão arterial sistêmica de causa essencial ou idiopática, num subgrupo de aproximadamente 15% podemos encontrar uma causa secundária, seja doença renal ou endócrina. Um correto diagnóstico de uma causa endócrina permite uma cura cirúrgica ou dramática resposta a terapia farmacológica apropriada. O diagnóstico e o tratamento das principais patologias endócrinas que cursam com hipertensão são revisados neste capítulo.